Clinical Value of the Biochemical Markers of Bone Remodeling in the Assessment of Bone Metabolic Diseases
نویسنده
چکیده
In clinical practice, low bone mineral densi ty (BMD) and, therefore, scarcity of bone mineral is identified and quantified by dual energy X-ray absorptio-metry (DXA) (1). However, BMD predicts only 66Ê74% of variance of the bone strength (2), and many individuals with normal areal BMD suffer fractures (3). It is well recognized that other aspects of bone composition and structure may contribute, independently of BMD, to bone strength and the risk of fracture. Bone strength is determined by the bone mass, geometry and quality of bone (4).
منابع مشابه
A Novel Study on Non-invasive Assessment of Renal Osteodystrophy among Iranian Hemodialysis Patients
Background: Renal osteodystrophy (ROD) is a common bone and mineral metabolism disorder in patients with end-stage renal disease (ESRD). This study aimed to determinate the frequency of the subtypes of ROD and evaluate the diagnostic value of biochemical as the well as radiographic markers for the diagnosis of ROD among hemodialysis patients in Golestan province of Iran. Materials and Methods...
متن کاملBiochemical markers of bone collagen type I metabolism.
This review focuses on the analysis of diagnostic value of the major bone remodeling markers, in particular synthesis and degradation markers of collagen type I. These include carboxy- and aminoterminal telopeptide, carboxy- and aminoterminal propeptide of procollagen type I, hydroxyproline, hydroxylysine, pyridinoline and deoxypyridinoline. Their measurement allows evaluating the structural an...
متن کاملClinical application of biochemical markers of bone turnover.
With the ageing population in most countries, disorders of bone and mineral metabolism are becoming increasingly relevant to every day clinical practice. Consequently, the interest in, and the need for effective measures to be used in the screening, diagnosis and follow-up of such pathologies have markedly grown. Together with clinical and imaging techniques, biochemical tests play an important...
متن کاملDesigning an Iran FRAX Model and Defining Intervention and Assessment Thresholds for Osteoporosis
Background and Objectives: The purpose of this study was to adopt and calibrate the fracture risk assessment algorithm FRAX® for the Iranian population and to provide the required guidance on how to apply it in clinical practice. Methods: The age-specific ten-year probability of major osteoporotic fractures was calculated in women with an average BMI to determine the fracture probability a...
متن کاملRadiographic Assessment of Bone Cortex to Bone Diameter Ratio of Radius, Tibia, Metacarpus, Metatarsus and Proximal Phalanx of Fore and Hindlimbs in Minature Donkey
Objective - The aim of this study was to measure the ratio of bone cortex (C) to bone diameter (D), (C/D) in radius/tibia, metacarpus /metatarsus and proximal phalanges in fore and hindlimbs to be used as a diagnostic guide in metabolic and nutritional diseases in Minature Donkey. Design- Experimental study Animals- Eight adult Minature donkeys. Procedures- Lateromedial, dorsopalmar and dors...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2006